Thank you for bringing this concern to our attention. We take it seriously and have thoroughly investigated the issue before responding. At Ipothecary, we prioritize delivering high-quality products.
Tween80, also known as Polysorbate 80, is a nonionic surfactant and emulsifier commonly used in pharmaceuticals, cosmetics, and food. It's GRAS (generally recognized as safe) by the FDA. Polysorbates help mix ingredients like oil and water, breaking down in your body through hydrolysis.
Safety assessments, including oral toxicity, mutagenicity, and carcinogenicity studies, indicate low toxicity levels. Skin testing and clinical use show little potential for irritation or adverse effects.
Polysorbate 80 has been assessed for safety in various ways:
Oral Toxicity:
Acute and long-term oral toxicity studies in animals indicate a low order of toxicity with oral ingestion of Polysorbates.
Mutagenicity:
Polysorbate 80 was shown to be non-mutagenic in the Ames and micronucleus tests.
Carcinogenicity:
The Polysorbates were found to be noncarcinogenic in laboratory animals. However, it's noted that they can enhance the activity of known chemical carcinogens without being carcinogenic themselves.
Skin Testing:
Clinical skin testing showed Polysorbates to have little potential for human skin irritation or evidence of skin sensitization or phototoxicity.
Clinical Use:
The available data suggest that Polysorbates are used in numerous preparations without significant clinical reports of adverse effects.
In Liposomal Gemmos, Tween 80 comprises less than 4%, which is crucial in stabilizing nanoparticles for product quality and ethical manufacturing. It prevents aggregation and degradation, ensuring nano-structure integrity throughout the shelf life.
The use of Tween 80, together with other ingredients, is grounded in its ability to stabilize nanomicelles, a crucial aspect of our nanoparticle-based supplements. This stabilization is not just a matter of maintaining product quality but also a matter of ethical manufacturing. By preventing the aggregation and degradation of nanoparticles, Tween 80 helps in maintaining the nano-structure of our supplements throughout their shelf life. This is essential to ensure that when our customers choose our products for their nano-based benefits, that is exactly what they receive.
“Our choice of Tween 80 is more than a technical decision; it is an ethical one. We believe in being transparent with our customers about how our products are made and what they contain.
We combine Tween 80 with plant stem cells to create a nanomicelle to ensure liposomal uptake of these powerful vibrational, drainage, and regenerative remedies.
The plant stem cells are made using the Spagyric extraction method. The Embryonic plant extracts - do not contain ANY heavy metals because they are not even exposed to the elements long enough- once they bud, they are picked within hours. These remedies are tested continuously by our manufacturer and are third-party tested by batch.” - Dr. Christine Schaffner
As noted above, what Tween80 is combined with that is essential… does it amplify absorption of a healthy ingredient or carcinogenic ingredient?
We apologize for any inconvenience and assure you that we are committed to providing the best for everyone on their wellness journeys. Please feel free to read more on how Tween 80 has been assessed for safety here as well: https://journals.sagepub.com/doi/10.3109/10915818409021272
- The Ipothecary Team
